Donatella Santini
S. Orsola - Malpighi
Via Massarenti, 9
40138 Bologna, ITALY
Biography
Donatella Santini, pathologist of the Department of Pathology, University of Bologna, IRCCS Policlinico di S. Orsola, Bologna, Italy from 1983 to 1/11/2023, since November 2023 she has been retired and continues to collaborate in the various IRCCS research projects of which she is PI or collaborator.
Dr. Santini presented works at different meetings since 1991 and contributed in different breast cancer workshops as well as she is an active investigator or co-investigator in several clinical trials in the area of Breast and Gynecological cancer.
She has extensive experience and in breast, gynecologic diseases and her activity is mainly focused on breast cancer bio-pathological characterization and Quality Assurance Program in breast pathology.
She is active part of a working group about breast and gynecologic tumor as an external supervisor for complex clinical situation and as expert second opinion activities.
She collaborates with the working groups of the regional oncology network appointed by the Emilia Romagna Region, Italy.
She collaborates with National and International Scientific Societies in defining recommendations or guidelines.
She has a particular interest in breast and gynecologic oncology documented by numerous works and publications.
Dr. Santini has participated in several projects at Bologna University, IRCCS Policilico S.Orsola, and National and International research group.
She gives periodical pathology and histological support to assist young resident from Italy and other countries.
She carried out an intense scientific activity focusing mainly on breast, female genital trac, endocrine and pancreatic disease; this activity took the form of scientific papers in national and international journals, attendance to conferences, publication of chapters of books and monographs, for a total of more than 350 scientific papers.
Most relevant papers
D. Santini
Di Dalmazi G, Morandi L, Rubin B, Pilon C, Asioli S, Vicennati V, De Leo A, Ambrosi F, Santini D, Pagotto U, Maffeis V, Fassina A, Fallo F
DNA Methylation of Steroidogenic Enzymes in Benign Adrenocortical Tumors: New Insights in Aldosterone-Producing Adenomas.
J Clin Endocrinol Metab. 2020 Dec 1;105(12)
D. Santini
Dondi G, Coluccelli S, De Leo A, Ferrari S, Gruppioni E, Bovicelli A, Godino L, Coada CA, Morganti AG, Giordano A, Santini D, Ceccarelli C, Turchetti D, De Iaco P, Perrone AM.
An Analysis of Clinical, Surgical, Pathological and Molecular Characteristics of Endometrial Cancer According to Mismatch Repair Status. A Multidisciplinary Approach.
Int J Mol Sci. 2020 Sep 29;21(19):7188.
D. Santini
59. Vanoli A, Grillo F, Guerini C, Neri G, Arpa G, Klersy C, Nesi G, Giuffrida P, Sampietro G, Ardizzone S, Fociani P, Fiocca R, Latella G, Sessa F, D'Errico A, Malvi D, Mescoli C, Rugge M, Ferrero S, Poggioli G, Rizzello F, Macciomei MC, Santini D, Volta U, De Giorgio R, Caio G, Calabrò A, Ciacci C, D'Armiento M, Rizzo A, Solina G, Martino M, Tonelli F, Villanacci V, Cannizzaro R, Canzonieri V, Florena AM, Biancone L, Monteleone G, Caronna R, Ciardi A, Elli L, Caprioli F, Vecchi M, D'Incà R, Zingone F, D'Odorico A, Lenti MV, Oreggia B, Reggiani Bonetti L, Giannone AG, Orlandi A, Barresi V, Ciccocioppo R, Amodeo G, Biletta E, Luinetti O, Pedrazzoli P, Pietrabissa A, Corazza GR, Solcia E, Paulli M, Di Sabatino A
Prognostic Role of Mismatch Repair Status, Histotype and High-Risk Pathologic Features in Stage II Small Bowel Adenocarcinomas.
Ann Surg Oncol. 2020 Aug
D. Santini
Cortesi L, Baldassarri B, Ferretti S, Razzaboni E, Bella M, Bucchi L, Canuti D, De Iaco P, De Santis G, Falcini F, Galli V, Godino L, Leoni M, Perrone AM, Pignatti M, Saguatti G, Santini D, Sassoli de'Bianchi P, Sebastiani F, Taffurelli M, Tazzioli G, Turchetti D, Zamagni C, Naldoni C
A regional population-based hereditary breast cancer screening tool in Italy: First 5-year results.
Cancer Med. 2020
D. Santini
De Leo A, Mosconi C, Zavatta G, Tucci L, Nanni C, Selva S, Balacchi C, Ceccarelli C, Santini D, Pantaleo MA, Minni F, Fanti S, Golfieri R, Pagotto U, Vicennati V, Di Dalmazi G.
Radiologically defined lipid-poor adrenal adenomas: histopathological characteristics.
J Endocrinol Invest. 2020
D. Santini
Giuffrida P, Arpa G, Grillo F, Klersy C, Sampietro G, Ardizzone S, Fociani P, Fiocca R, Latella G, Sessa F, D'Errico A, Malvi D, Mescoli C, Rugge M, Nesi G, Ferrero S, Furlan D, Poggioli G, Rizzello F, Macciomei MC, Santini D, Volta U, De Giorgio R, Caio G, Calabrò A, Ciacci C, D'Armiento M, Rizzo A, Solina G, Martino M, Tonelli F, Villanacci V, Cannizzaro R, Canzonieri V, Florena AM, Biancone L, Monteleone G, Caronna R, Ciardi A, Elli L, Caprioli F, Vecchi M, D'Incà R, Zingone F, D'Odorico A, Lenti MV, Oreggia B, Reggiani Bonetti L, Astegiano M, Biletta E, Cantoro L, Giannone AG, Orlandi A, Papi C, Perfetti V, Quaquarini E, Sandri G, Silano M, Usai P, Barresi V, Ciccocioppo R, Luinetti O, Pedrazzoli P, Pietrabissa A, Viglio A, Paulli M, Corazza GR, Solcia E, Vanoli A, Di Sabatino A.
PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability.
Mod Pathol. 2020
D. Santini
Basturk O, Weigelt B, Adsay V, Benhamida JK, Askan G, Wang L, Arcila ME, Zamboni G, Fukushima N, Gularte-Mérida R, Da Cruz Paula A, Selenica P, Kumar R, Pareja F, Maher CA, Scholes J, Oda Y, Santini D, Doyle LA, Petersen I, Flucke U, Koelsche C, Reynolds SJ, Yavas A, Deimling AV, Reis-Filho JS, Klimstra DS.
Sclerosing epithelioid mesenchymal neoplasm of the pancreas - a proposed new entity.
Mod Pathol. 2020 Mar;33(3):456-46
D. Santini
Rubio IT, Wyld L, Marotti L, Athanasiou A, Regitnig P, Catanuto G, Schoones Ma JW, Zambon M, Camps J, Santini D, Dietz J, Sardanelli F, Varga Z, Smidt M, Sharma N, Shaaban AM, Gilbert F
European guidelines for the diagnosis, treatment and follow-up of breast lesions with uncertain malignant potential (B3 lesions) developed jointly by EUSOMA, EUSOBI, ESP (BWG) and ESSO.
Eur J Surg Oncol. 2023 Nov 27;50(1):107292.
D. Santini
Aristei C, Tomatis M, Antonio Ponti, Marotti L, Cardoso MJ, Cheung KL, Curigliano G, De Vries J, Santini D, Sardanelli F, Van Dam P, Rubio IT; EUSOMA Working group
Treatment and outcomes in breast cancer patients: A cross section study from the EUSOMA breast centre network.
Eur J Cancer. 2024 Jan;196:
D. Santini
Dajti G, Serra M, Cisternino G, Ceccarelli C, Pellegrini A, Melina M, De Leo A, Santini D, Taffurelli M, Zanotti S
Prognostic Role of p53 Immunohistochemical Status in invasive Breast Cancer. A Retrospective Review of 1387 Cases With Luminal-Like/Her2 Negative Breast Tumors.
Oncologist. 2023 Nov 23:oyad309.
D. Santini
Mazzitelli C, Santini D, Corradini AG, Zamagni C, Trerè D, Montanaro L, Taffurelli M.
Liquid Biopsy in the Management of Breast Cancer Patients: Where Are We Now and Where Are We Going.
Diagnostics (Basel). 2023 Mar 25;13(7):1241
D. Santini
Innella G, Godino L, Erini G, De Leo A, Santini D, Perrone AM, De Iaco P, Zamagni C, Turchetti D.
Factors predicting BRCA1/2 pathogenic variants in patients with ovarian cancer: a systematic review with meta-analysis.
J Clin Pathol. 2023 Aug;76(8):510-517
D. Santini
Pruneri G, Lorenzini D, Mastropasqua MG, Perrone G, Rizzo A, Santini D, Volpi CC, Cinieri S, Zambelli A, Sapino A, Castellano I.
The central role of pathology labs in breast cancer precision oncology: a call for action.
NPJ Breast Cancer. 2023 Jan 25;9(1):3
D. Santini
de Biase D, Maloberti T, Corradini AG, Rosini F, Grillini M, Ruscelli M, Coluccelli S, Altimari A, Gruppioni E, Sanza V, Turchetti D, Galuppi A, Ferioli M, Giunchi S, Dondi G, Tesei M, Ravegnini G, Abbati F, Rubino D, Zamagni C, De Iaco P, Santini D, Ceccarelli C, Perrone AM, Tallini G, De Leo A.
Integrated clinicopathologic and molecular analysis of endometrial carcinoma: Prognostic impact of the new ESGO-ESTRO-ESP endometrial cancer risk classification and proposal of histopathologic algorithm for its implementation in clinical practice.
Front Med (Lausanne). 2023 Mar 30;10:114649
D. Santini
Ruscelli M, Maloberti T, Corradini AG, Rosini F, Querzoli G, Grillini M, Altimari A, Gruppioni E, Sanza V, Costantino A, Ciudino R, Errani M, Papapietro A, Coluccelli S, Turchetti D, Ferioli M, Giunchi S, Dondi G, Tesei M, Ravegnini G, Abbati F, Rubino D, Zamagni C, D'Angelo E, De Iaco P, Santini D, Ceccarelli C, Perrone AM, Tallini G, de Biase D, De Leo A.
Prognostic Impact of Pathologic Features in Molecular Subgroups of Endometrial Carcinoma.
J Pers Med. 2023 Apr 25;13(5):723
D. Santini
Barbero G, Zuntini R, Magini P, Desiderio L, Bonaguro M, Perrone AM, Rubino D, Grippa M, De Leo A, Ceccarelli C, Godino L, Miccoli S, Ferrari S, Santini D, De Iaco P, Zamagni C, Innella G, Turchetti D.
Characterization of BRCA Deficiency in Ovarian Cancer.
Cancers (Basel). 2023 Feb 28;15(5):1530.
