ServiziMenu principaleHome

Kwok - Leung Cheung

Kwok-Leung Cheung
Royal Derby Hospital Centre
Uttoxeter Road


Professor Cheung is Deputy Head of Education and Director of The BMBS Medicine Programmes, and Professor of Breast Surgery and Medical Education at the University of Nottingham, UK.
Following undergraduate medical education and general surgery training at the University of Hong Kong Medical Centre, he conducted translational research at the University of Nottingham, with a Doctor of Medicine awarded in 2001. He then took up the post of Consultant Breast Surgeon at Nottingham University Hospitals where he served as Head of Service, Breast Services (2007-2010) and Lead Clinician for Breast Cancer (2007-2011). He joined the University as a clinical academic in 2004.
Professor Cheung is currently Honorary Consultant Breast Surgeon at the University Hospitals of Derby and Burton.
He obtained surgical fellowship status from Hong Kong, Edinburgh and America. He is also a Senior Fellow of the Higher Education Academy. Professor Cheung was selected as one of the 12 International Guest Scholars 2007 of the American College of Surgeons, as a recognition of his strong interests and commitment in teaching and research. Professor Cheung is a member of the Faculty of Examiners for Intercollegiate MRCS and the Panel of Examiners of the Intercollegiate Specialty Board
in General Surgery. He is also part of the National Cancer Peer Review team and an External Professional Advisor to the Parliamentary Health Service Ombudsman. Professor Cheung is a member of the Association of Breast Surgery, British Breast Group, British Association of Cancer Surgery, European Society of Breast Cancer Specialists (EUSOMA), American Society of Clinical Oncology, and International Society of Geriatric Oncology (SIOG). In 2015, he received the National Representative of the Year award from SIOG recognising his commitments to geriatric oncology and SIOG. Within SIOG, he is the Treasurer, Member of the Executive Committee and of the Board, and the UK National Representative. Furthermore, he is currently a Member of the Breast Cancer
Guidelines Committee of the National Institute for Health and Care Excellence (NICE) and of the Surgical Specialty Board in General Surgery at the Royal College of Surgeons of Edinburgh.
In 2010, Professor Cheung pioneered the Symposium on Primary Breast Cancer in Older Women, the first of its kind in the UK, which has now become a biennial event, hosted by the University in association with SIOG. He is also a member of the Management Committee of the Nottingham Breast Cancer Research Centre, launched in 2018.
Professor Cheung’s key research interests include breast cancer and geriatric oncology. He is the author/co-author of around 200 journal articles and book chapters.
Specifically to EUSOMA, he joined the society in 1996, and has supervised a EUSOMA fellow (2008) and been actively participating in joint EUSOMA/SIOG initiatives – Roundtable discussion on ‘Treatment of axillary lymph nodes in older patients with breast cancer’ (2016) and co-authoring the ‘Updated recommendations regarding the management of older patients with breast cancer’ (published in Lancet Oncology in 2021). He was elected in 2020 to join the Executive Committee.
During this term, Professor Cheung has contributed specifically in one of the work packages in the Innovative collaboration for Inter-specialty cancer training across Europe (INTERACT-EUROPE) and as a Councillor of the Accreditation Council of Oncology in Europe (ACOE). Professor Cheung also leads a research project investigating the disparity of breast reconstruction in the older population across Europe.

Most relevant papers

K. Cheung
Robertson JFR, Bondarenko IM, Trishkina E, Dvorkin M, Panasci L, Manikhas A, Shparyk Y, Cardona-Huerta S, Cheung KL, Philco-Salas MJ, Ruiz-Borrego M, Shao Z, Noguchi S, Rowbottom J, Stuart M, Grinsted LM, Fazal M, Ellis MJ.
Fulvestrant 500 mg versus anastrozole 1 mg for hormone receptor-positive advanced breast cancer (FALCON): an international, randomised, double-blind, phase 3 trial.
Lancet. 2016 Dec 17;388(10063):2997-3005. doi: 10.1016/S0140-6736(16)32389-3. Epub 2016 Nov 29.PMID: 27908454

K. Cheung
Syed BM, Green AR, Ellis IO, Cheung KL.
Human epidermal growth receptor-2 overexpressing early operable primary breast cancers in older (>=70 years) women: biology and clinical outcome in comparison with younger (<70 years) patients.
Ann Oncol. 2014 Apr;25(4):837-842. doi: 10.1093/annonc/mdu028.PMID: 24667716 Free article.

K. Cheung
Johnston SR, Kilburn LS, Ellis P, Dodwell D, Cameron D, Hayward L, Im YH, Braybrooke JP, Brunt AM, Cheung KL, Jyothirmayi R, Robinson A, Wardley AM, Wheatley D, Howell A, Coombes G, Sergenson N, Sin HJ, Folkerd E, Dowsett M, Bliss JM; SoFEA investigators.
Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentre, phase 3 randomised trial.
Lancet Oncol. 2013 Sep;14(10):989-98. doi: 10.1016/S1470-2045(13)70322-X. Epub 2013 Jul 29.PMID: 23902874

K. Cheung
Johnston SJ, Kenny FS, Syed BM, Robertson JF, Pinder SE, Winterbottom L, Ellis IO, Blamey RW, Cheung KL.
A randomised trial of primary tamoxifen versus mastectomy plus adjuvant tamoxifen in fit elderly women with invasive breast carcinoma of high oestrogen receptor content: long-term results at 20 years of follow-up.
Ann Oncol. 2012 Sep;23(9):2296-300. doi: 10.1093/annonc/mdr630. Epub 2012 Feb 21.PMID: 22357257

K. Cheung
Syed BM, Johnston SJ, Wong DW, Green AR, Winterbottom L, Kennedy H, Simpson N, Morgan DA, Ellis IO, Cheung KL.
Long-term (37 years) clinical outcome of older women with early operable primary breast cancer managed in a dedicated clinic.
Ann Oncol. 2012 Jun;23(6):1465-71. doi: 10.1093/annonc/mdr446. Epub 2011 Oct 14.PMID: 22003241

K. Cheung
Khoury EG, Nuamek T, Heritage S, Fulton-Ward T, Kucharczak J, Ng C, Kalsi T, Gomes F, Lind MJ, Battisti NML, Cheung KL, Parks R, Pearce J, Baxter MA.
Geriatric Oncology as an Unmet Workforce Training Need in the United Kingdom-A Narrative Review by the British Oncology Network for Undergraduate Societies (BONUS) and the International Society of Geriatric Oncology (SIOG) UK Country Group.
Cancers (Basel). 2023 Sep 28;15(19):4782. doi: 10.3390/cancers15194782.PMID: 37835476 Free PMC article. Review.

K. Cheung
Chan KS, Chong MTH, Chia CLK, Cheung KL.
Revisiting primary endocrine therapy versus surgery in older women with breast cancer: meta-analysis.
Br J Surg. 2023 Mar 30;110(4):420-431. doi: 10.1093/bjs/znac435.PMID: 36718056

K. Cheung
Biganzoli L, Battisti NML, Wildiers H, McCartney A, Colloca G, Kunkler IH, Cardoso MJ, Cheung KL, de Glas NA, Trimboli RM, Korc-Grodzicki B, Soto-Perez-de-Celis E, Ponti A, Tsang J, Marotti L, Benn K, Aapro MS, Brain EGC.
Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists (EUSOMA) and the International Society of Geriatric Oncology (SIOG).
Lancet Oncol. 2021 Jul;22(7):e327-e340. doi: 10.1016/S1470-2045(20)30741-5. Epub 2021 May 14.PMID: 34000244 Review

K. Cheung
Wyld L, Reed MWR, Collins K, Burton M, Lifford K, Edwards A, Ward S, Holmes G, Morgan J, Bradburn M, Walters SJ, Ring A, Robinson TG, Martin C, Chater T, Pemberton K, Shrestha A, Nettleship A, Murray C, Brown M, Richards P, Cheung KL, Todd A, Harder H, Brain K, Audisio RA, Wright J, Simcock R, Armitage F, Bursnall M, Green T, Revell D, Gath J, Horgan K, Holcombe C, Winter M, Naik J, Parmeshwar R, Gosney M, Hatton M, Thompson AM.
Bridging the age gap in breast cancer: cluster randomized trial of two decision support interventions for older women with operable breast cancer on quality of life, survival, decision quality, and treatment choices.
Surg. 2021 May 27;108(5):499-510. doi: 10.1093/bjs/znab005.PMID: 33760077 Free PMC article. Clinical Trial.

K. Cheung
Extermann M, Brain E, Canin B, Cherian MN, Cheung KL, de Glas N, Devi B, Hamaker M, Kanesvaran R, Karnakis T, Kenis C, Musolino N, O'Donovan A, Soto-Perez-de-Celis E, Steer C, Wildiers H
Priorities for the global advancement of care for older adults with cancer: an update of the International Society of Geriatric Oncology Priorities Initiative.
International Society of Geriatric Oncology. Lancet Oncol. 2021 Jan;22(1):e29-e36. doi: 10.1016/S1470-2045(20)30473-3.PMID: 33387502 Review.